2008;43(7):653-657. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. Cancer Res 2001;61:3647-52.. View abstract. Vinceti M, Filippini T, Del Giovane C, et al. Plasma selenium level before diagnosis and the risk of prostate cancer development. Other research shows that taking selenium alone or with other nutrients does not reduce lung cancer risk. View abstract. View abstract. View abstract. Ardestani Zadeh A, Arab D, Kia NS, et al. Br.J Nutr. Nutr Cancer 2011;63(8):1185-95. Vinceti M, Dennert G, Crespi CM, et al. Excess melanoma incidence in a cohort exposed to high levels of environmental selenium. Apostolidis, N. S., Panoussopoulos, D. G., Stamou, K. M., Kekis, P. B., Paradellis, T. P., Karydas, A. G., Zarkadas, C., Zirogiannis, P. N., and Manouras, A. J. Selenium metabolism in patients on continuous ambulatory peritoneal dialysis. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations. Crit Care 2006;10(6):R153. Wichman J, Winther KH, Bonnema SJ, Hegedüs L. Selenium supplementation significantly reduces thyroid autoantibody levels in patients with chronic autoimmune thyroiditis: a systematic review and meta-analysis. Crit Rev Food Sci Nutr 2020;60(4):684-94. doi: 10.1080/10408398.2018.1548427. J Natl Cancer Inst 2000;92:2018-23.. View abstract. Blood infection (sepsis). Efficacy of Long-term Selenium Supplementation in the Treatment of Chronic Keshan Disease with Congestive Heart Failure. Eur J Clin Nutr 2001;55(4):293-297. Impact of treatment planning target volumen (PTV) size on radiation induced diarrhea following selenium supplementation in gynecologic radiation oncology-a subgroup analysis of a multicenter, phase III trial. View abstract. View abstract. J Natl Cancer Inst 2004;96:645-7. View abstract. Ebselen Study Group. Smith DK, Feldman EB, Feldman DS. Duffield AJ, Thomson CD, Hill KE, Williams S. An estimation of selenium requirements for New Zealanders. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, Latest Research on Advanced Prostate Cancer. 2002;13(2):94-105. Curr.Opin.Clin.Nutr.Metab Care 2008;11(3):261-266. J Clin Gastroenterol 2001;32:405-8. View abstract. View abstract. View abstract. Are There Side Effects of Egg Whites? View abstract. J Trace Elem.Med Biol. Cochrane Database Syst Rev. Block, K. I., Koch, A. C., Mead, M. N., Tothy, P. K., Newman, R. A., and Gyllenhaal, C. Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials. 2004;(4):CD004183. Effect of reproduction on the bioavailability of calcium, zinc and selenium. Schrauzer GN, Sacher J. Selenium in the maintenance and therapy of HIV-infected patients. Effect of selenium supplementation on biochemical markers and outcome in critically ill patients. Reduction of nosocomial pneumonia after major burns by trace element supplementation: aggregation of two randomised trials. Nutr.Cancer 1999;34(2):167-172. Chatterjee S, Combs GF Jr, Chattopadhyay A, Stolzenberg-Solomon R. Serum selenium and pancreatic cancer: a prospective study in the Prostate, Lung, Colorectal and Ovarian Cancer Trial cohort. Br.J Nutr. Lancet 2000;356:233-41. J Nutr. Early research shows that taking a selenium supplement along with a probiotic supplement improves depression, anxiety, and stress by a small amount in women with PCOS. View abstract. Selenium Supplementation for Prevention of Colorectal Adenomas and Risk of Associated Type 2 Diabetes. Some evidence shows that taking selenium daily for up to 2 years can slow how quickly HIV spreads and can increase immune function. View abstract. View abstract. AOX. View abstract. Bonomini, M., Forster, S., De Risio, F., Rychly, J., Nebe, B., Manfrini, V., Klinkmann, H., and Albertazzi, A. Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions. Do antioxidants prevent colorectal cancer? Hawkes, W. C., Richter, B. D., Alkan, Z., Souza, E. C., Derricote, M., Mackey, B. E., and Bonnel, E. L. Response of selenium status indicators to supplementation of healthy North American men with high-selenium yeast. BMJ 5-14-2005;330(7500):1109. Margaritis, I., Palazzetti, S., Rousseau, A. S., Richard, M. J., and Favier, A. Antioxidant supplementation and tapering exercise improve exercise-induced antioxidant response. View abstract. Rayman, M., Thompson, A., Warren-Perry, M., Galassini, R., Catterick, J., Hall, E., Lawrence, D., and Bliss, J. Micronutrient supplements: toxicity and drug interactions. Influence of hemodialysis on selenium blood levels. Tolerable Upper Intake Levels (UL) for Selenium per Day View abstract. Selenium alone seems to protect against recurrence of only certain type of advanced polyps. Information from this source is evidence-based and objective, and without commercial influence. You may report them to the FDA. The dose medicines in this class will be different for different patients. Balaz C, Feher J. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. J Int Assoc.Physicians AIDS Care (Chic.) Eur.J Clin.Nutr. Phase III randomised chemoprevention study with selenium on the recurrence of non-invasive urothelial carcinoma. Side effects of consumption of too much of this mineral include garlic odor in breath, lung problems, breathlessness gastrointestinal irritation, stomach upsets, nausea, vomiting, diarrhea, stomach pain, fatigue, muscle cramps, restlessness, listlessness, dementia, behavioral problems, metallic taste in the mouth, hair loss, skin inflammation, tooth decay, and fingernail discoloration. New approaches to assess selenium status and requirement. 9-5-2006;145(5):372-385. Koskelo EK. Adv.Exp.Med Biol. Mark SD, Wang W, Fraumeni JF Jr, et al. View abstract. The body breaks down medications to get rid f them. View abstract. Cochrane Database Syst Rev 2013;1:CD009671. 2017. View abstract. Eur J Clin Nutr 1990;44:799-802. Eur J Cancer. Diarrhea. Am.J Clin.Nutr. The clinical outcomes of selenium supplementation on critically ill patients: A meta-analysis of randomized controlled trials. Other research suggests that selenium, taken alone or with other nutrients, does not reduce the risk of death. View abstract. View abstract. Am.J.Clin.Nutr. Cochrane.Database.Syst.Rev. Biol.Trace Elem.Res. View abstract. Urology 2007;69(6):1102-1106. Beck MA, Nelson HK, Shi Q, et al. Am J Clin Nutr 2004;80:410-6. Aggarwal R, Gathwala G, Yadav S, Kumar P. Selenium Supplementation for Prevention of Late-Onset Sepsis in Very Low Birth Weight Preterm Neonates. Clin Lab Med 1998;18:673-85. Br J Nutr 1997;77:551-63.. View abstract. AIDS 1999;13:495-500. Does dietary intake of selenium protect against cancer? Birth control pills (Contraceptive drugs) interacts with SELENIUM. View abstract. Varikasuvu SR, Prasad V S, Kothapalli J, Manne M. Brain Selenium in Alzheimer's Disease (BRAIN SEAD Study): a Systematic Review and Meta-Analysis. See KA, Lavercombe PS, Dillon J, Ginsberg R. Accidental death from acute selenium poisoning. Selenium-induced protection against cis-diamminedichloroplatinum(II) nephrotoxicity in mice and rats. Katzen-Luchenta, J. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Selenium is safe for most of us when taken orally in amounts under 400 mcg each day. Transplant Proc 2001;33:974-5. 1990;29(3):211-213. Cancer-protective properties of high-selenium broccoli. Bardia, A., Tleyjeh, I. M., Cerhan, J. R., Sood, A. K., Limburg, P. J., Erwin, P. J., and Montori, V. M. Efficacy of antioxidant supplementation in reducing primary cancer incidence and mortality: systematic review and meta-analysis. Evans, J. R. and Henshaw, K. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. 1991;53(3):748-754. Early research in China suggests that taking selenium for 2-5 years can reduce the occurrence of liver cancer. Peretz A, Siderova V, Neve J. Selenium supplementation in rheumatoid arthritis investigated in a double blind, placebo-controlled trial. Colon cancer, rectal cancer. View abstract. All rights reserved. View abstract. This information may not fit your specific health circumstances. N Engl J Med 2001;345:1583-93. ), allergies, pre-existing diseases, and current health conditions (e.g. View abstract. The effect of selenium therapy on mortality in patients with sepsis syndrome: A systematic review and meta-analysis of randomized controlled trial. A., Dean, J. M., Holubkov, R., Berger, J., Meert, K. L., Anand, K. J., Zimmerman, J., Newth, C. J., Harrison, R., Burr, J., Willson, D. F., and Nicholson, C. The randomized comparative pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial. However, some research suggests that taking 100 mcg of selenium along with zinc, vitamin C, vitamin E, and beta-carotene daily for 7.5 years might lower the risk of death from any cause in men, but not women. There is contradictory evidence about the effect of selenium supplements on HIV. Cheung MC, Zhao XQ, Chait A, et al. Use of selenium-silymarin mix reduces lower urinary tract symptoms and prostate specific antigen in men. Int.J Cancer 9-15-2008;123(6):1227-1239. View abstract. Serwin, A. Serum levels of selenium, manganese, copper, and iron in colorectal cancer patients. View abstract. Trace element status in multiple sclerosis. Prog Food Nutr Sci 1990;14:277-331. Smolkova, B., Dusinska, M., Raslova, K., Barancokova, M., Kazimirova, A., Horska, A., Spustova, V., and Collins, A. Folate levels determine effect of antioxidant supplementation on micronuclei in subjects with cardiovascular risk. Thyroid function parameters during a selenium repletion/depletion study in phenylketonuric subjects. View abstract. Selenium is a crucial part of a number of enzymes, a substance made by your body to help bring about a specific reaction. Burk, R. F. and Hill, K. E. Selenoprotein P: an extracellular protein with unique physical characteristics and a role in selenium homeostasis. Sutter ME, Thomas JD, Brown J, Morgan B. Selenium toxicity: a case of selenosis caused by a nutritional supplement. It is not known if selenium alone decreases the effectiveness of some medications used for lowering cholesterol. View abstract. Manzanares W, Lemieux M, Elke G, Langlois PL, Bloos F, Heyland DK. View abstract. Zhonghua Yu Fang Yi.Xue.Za Zhi. 2016;20(1):356. View abstract. Baldew GS, van den Hamer CJ, Los G, et al. View abstract. Wasowicz W, Gromadzinska J, Szram K, et al. View abstract. View abstract. Critically elucidating the role of selenium. View abstract. View abstract. 2001;6(1):20-47. Research shows that taking selenium reduces insulin resistance but does not improve blood sugar or kidney function in people with kidney disease and diabetes. Carcillo, J. View abstract. View abstract. View abstract. Environ Sci Technol 2012;46(20):11313-8. Pediatr.Res. Overactive thyroid (hyperthyroidism). Cochrane Database Syst Rev 2004;(4):CD003703. Sedative medications (Barbiturates) interacts with SELENIUM. 2018 Sep;33(9):789-810. Cochrane Database Syst Rev 2006;(3):CD005037. Breast J 2000;6:14-19.. View abstract. View abstract. 1989;258:45-58. View abstract. View abstract. Scand Cardiovasc J 2013;47(2):80-7. View abstract. Heyland, D. K., Dhaliwalm, R., Day, A., Drover, J., Cote, H., and Wischmeyer, P. Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study. 2008;(3):CD004183. Wink J, Giacoppe G, King J. 1995;37(5):468-469. 5-28-2010;141(2):e26-e27. J Clin Endocrinol Metab. Stevic, Z., Nicolic, A., and Blagojevic, D. A controlled trial of combination of methionine and antioxidants in ALS patients. JAMA 1996;276:1957-63. View abstract. View abstract. J Crit Care 2014;29(1):150-6. Science peels the onion of selenium effects on prostate carcinogenesis. 3-21-2012;104(6):488-492. J Gen.Intern Med 2006;21(7):735-744. Hofstad, B., Almendingen, K., Vatn, M., Andersen, S. N., Owen, R. W., Larsen, S., and Osnes, M. Growth and recurrence of colorectal polyps: a double-blind 3-year intervention with calcium and antioxidants. View abstract. View abstract. View abstract. Selenium deficiency mitigates hypothyroxinemia in iodine-deficient subjects. Taking selenium along with these other vitamins might decrease the how well niacin works for increasing good cholesterol. Stein TP, Schluter MD, Leskiw MJ, Boden G. Attenuation of the protein wasting associated with bed rest by branched-chain amino acids. The amount of medicine that you take depends on the strength of the medicine. View abstract. Spiller, H. A. and Pfiefer, E. Two fatal cases of selenium toxicity. View abstract. Voitsekhovskaia, IuG, Skesters, A., Orlikov, G. A., Silova, A. 1997;31(6):358-361. Ann Pharmacother 1995;29;1302. Clin Nutr 2007;26(1):41-50. Expert.Opin Investig.Drugs 2005;14(9):1145-1155. View abstract. A secondary analysis of a randomized clinical trial. View abstract. Selenium is an essential trace mineral that plays a vital role in making antioxidant enzymes. Antioxidant supplement and long-term reduction of recurrent adenomas of the large bowel. 1989;69(4):359-362. Dawson EB, Albers JH, McGanity WJ. Neve J. Selenium supplementation for the primary prevention of cardiovascular disease. View abstract. Available for Android and iOS devices. View abstract. A., Gudino, A., Spate, V., and Karagas, M. R. Prediagnostic serum selenium concentration and the risk of recurrent colorectal adenoma: a nested case-control study. Biomed Khim. The effect of antioxidant supplementation on hepatitis C viral load, transaminases and oxidative status: a randomized trial among chronic hepatitis C virus-infected patients. Early research suggests that taking 200 mcg of selenium daily with or without coenzyme Q10 for 3 months does not improve symptoms of statin-induced myopathy. J Pediatr Endocrinol Metab 2012;25(7-8):639-44. View abstract. Effects of captopril and enalapril on zinc metabolism in hypertensive patients. J Infect Dis 2000;182 Suppl 1:S69-73. Early research suggests that taking 500 mcg of selenium on days of radiation therapy and 300 mcg on days without treatments reduces diarrhea by about 54%. Arch Intern Med 2007;167:148-54. Schrauzer, G. N. The nutritional significance, metabolism and toxicology of selenomethionine. Morgia G, Russo G, Voce S, et al. Muscle weakness caused by statin drugs (statin-induced myopathy). Sci Rep. 2016;6:19213. Arch Dis Child Fetal Neonatal Ed 1996;74(3):F158-F164. Some side effects may not be reported. View abstract. Christen WG, Glynn RJ, Gaziano JM, et al. JAMA 2013;310(20):2154-63. Cancer Causes Control. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. Dias MF, Sousa E, Cabrita S, et al. Pfeiffer, J. M., Askew, E. W., Roberts, D. E., Wood, S. M., Benson, J. E., Johnson, S. C., and Freedman, M. S. Effect of antioxidant supplementation on urine and blood markers of oxidative stress during extended moderate-altitude training. Evidence is conflicting about the effect of selenium on pancreatitis. Vanderpas JB, Contempre B, Duale NL, et al. FASEB J 2009;23(9):3233-3242. Cancer Epidemiol Biomarkers Prev 1998;7:853-6. Ishikawa M, Sasaki M, Koiwai K, et al. Clin Exp.Allergy 2007;37(2):180-187. 2018;1:CD005195. Vet.Hum.Toxicol. View abstract. 2018 Sep 14;11(1):80. Effects on the Circadian Rhythm. Scientists are studying selenium to understand how it affects health. J.Natl.Cancer Inst. 1998;62(1-2):1-6. Neurosurgery 1998;42(2):269-277. Liver cancer. View abstract. 1998;82(1):76-80. The effect of selenium supplementation on outcome in very low birth weight infants: a randomized controlled trial. Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the General Population Trial in Linxian, China. Curr Sci 2001;81:1215-8. 2018 Sep;150(3):478-486. doi: 10.1016/j.ygyno.2018.07.001. Navarro-Alarcon, M. and Cabrera-Vique, C. Selenium in food and the human body: a review. DeKosky ST, Schneider LS. Some birth control pills include ethinyl estradiol and levonorgestrel (Triphasil), ethinyl estradiol and norethindrone (Ortho-Novum 1/35, Ortho-Novum 7/7/7), and others. HIV.Clin.Trials 2002;3(6):483-491. 2002;5(6):363-374. Swelling (inflammation) of the pancreas (pancreatitis). View abstract. Biol Trace Elem Res 1998;65:143-51.. View abstract. Impact of selenium on mood and quality of life: a randomized, controlled trial. Bjelakovic, G., Nikolova, D., Simonetti, R. G., and Gluud, C. Antioxidant supplements for preventing gastrointestinal cancers. Srivastava, K. C. Ascorbic acid enhances the formation of prostaglandin E1 in washed human platelets and prostacyclin in rat aortic rings. Lack of interaction at the pharmacokinetic level of both compounds. Pan, S. Y., Ugnat, A. M., Mao, Y., Wen, S. W., and Johnson, K. C. A case-control study of diet and the risk of ovarian cancer. View abstract. Cancer Epidemiol.Biomarkers Prev. View abstract. Cancer Epidemiol.Biomarkers Prev. But some research shows that selenium reduces the risk of colon and rectal cancer in some patients. Schneider, M., Forster, H., Boersma, A., Seiler, A., Wehnes, H., Sinowatz, F., Neumuller, C., Deutsch, M. J., Walch, A., Hrabe de, Angelis M., Wurst, W., Ursini, F., Roveri, A., Maleszewski, M., Maiorino, M., and Conrad, M. Mitochondrial glutathione peroxidase 4 disruption causes male infertility. Fairris, G. M., Lloyd, B., Hinks, L., Perkins, P. J., and Clayton, B. E. The effect of supplementation with selenium and vitamin E in psoriasis. Arsenic poisoning. View abstract. Research shows that taking up to 200 mcg of selenium daily along with thyroid, A disorder that affects the bones and joints, usually in people with selenium deficiency (Kashin-Beck disease). View abstract. Z.Gesamte Inn.Med 1991;46(5):145-149. Kamble, P., Mohsin, N., Jha, A., Date, A., Upadhaya, A., Mohammad, E., Khalil, M., Pakkyara, A., and Budruddin, M. Selenium intoxication with selenite broth resulting in acute renal failure and severe gastritis. Cochrane Database Syst Rev 2014;3:CD005195. Meyer F, Galan P, Douville P, et al. Intensive Care Med 2004;30(suppl):S61. [Selenium as a trace element]. J Acquir.Immune.Defic.Syndr. VIT. Rayman, M. P. The use of high-selenium yeast to raise selenium status: how does it measure up? Am J Emerg Med 2013;31(8):1170-5. Int J Psychiatry Med 2003;33(1):55-69. View abstract. Arnaud J, Malvy D, Richard MJ, et al. View abstract. Available at: https://www.nap.edu/books/0309069351/html/. It might also cause Kashin-Beck disease, a type of arthritis that produces pain, swelling, and loss of motion in your joints. Taking 100 mcg of selenium daily for up to 24 weeks does not seem to improve quality of life, lung function, asthma symptoms, or inhaler use in people with asthma. View abstract. Watanabe C, Kim CY, Satoh H. Tissue-specific modification of selenium concentration by acute and chronic dexamethasone administration in mice. Selenium supplementation and lung cancer incidence: an update of the nutritional prevention of cancer trial. Adams ME. View abstract. View abstract. Chevallier A. Encyclopedia of Medicinal Plants. Biol Trace Elem Res 2019;191(2):331-7. doi: 10.1007/s12011-019-1636-7. Clinical and Experimental Medical Journal 2009;3:269-77. Eur.J Clin Nutr 1994;48(9):633-642. Br.J Rheumatol. View abstract. Also, selenium might work better in people with lower blood levels of selenium before treatment. View abstract. You WC, Brown LM, Zhang L, et al. View abstract. View abstract. Biofactors 2003;19:165-70. View abstract. Vernie LN, de Goeij JJ, Zegers C, et al. Accessed on June 26, 2020. Tessier, F., Hida, H., Favier, A., and Marconnet, P. Muscle GSH-Px activity after prolonged exercise, training, and selenium supplementation. Kidney damage in people with diabetes (diabetic nephropathy). J Clin Endocrinol Metab 2002;87:1687-91.. View abstract. Skin cancer. Ovarian cancer. View abstract. Selenium helps restore an imbalanced circadian … Daniels, L., Gibson, R., and Simmer, K. Randomised clinical trial of parenteral selenium supplementation in preterm infants. View abstract. View abstract. Toulis KA, Anastasilakis AD, Tzellos TG, et al. Gold salts bind to selenium and decrease selenium in parts of the body. View abstract. Dennert G, Horneber M. Selenium for alleviating the side effects of chemotherapy, radiotherapy and surgery in cancer patients. Darlow, B. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . Functional deterioration and selenium-vitamin E treatment in myotonic dystrophy. 02P-0457). View abstract. Berger MM, Binnert C, Baines M, et al. View abstract. FDA. Baum MK, Campa A, Lai S, et al. Hypertens.Pregnancy. Ketogenic diet: Rapid onset of selenium deficiency-induced cardiac decompensation. Antioxidant vitamin and mineral supplementation and prostate cancer prevention in the SU.VI.MAX trial. Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. 10-30-1990;110(26):3350-3351. Selenium deficiency increases the pathology of an influenza virus infection. Low selenium levels are associated with increased risk for osteoarthritis of the knee. View abstract. View abstract. Lippmann SM, Klein EA, Goodman PJ, et al. Neve J. Selenium as a risk factor for cardiovascular diseases. Failure of selenium-ace to improve osteoarthritis. Chemoprevention of colon cancer by a glutathione conjugate of 1,4-phenylenebis(methylene)selenocyanate, a novel organoselenium compound with low toxicity. Benton, D. and Cook, R. The impact of selenium supplementation on mood. 2008;36(1):131-144. View abstract. A type of inflammatory bowel disease (ulcerative colitis). View abstract. Sci Total Environ 2018;635:390-6. Cancer of the esophagus. Can J Physiol Pharmacol 2013;91(2):165-70. Meltzer, H. M., Norheim, G., Bibow, K., Myhre, K., and Holm, H. The form of selenium determines the response to supplementation in a selenium replete population. Kelly P, Musonda R, Kafwembe E, et al. But it might reduce the chance of an infection called sepsis. View abstract. VIT. View abstract. Benton, D. and Cook, R. Selenium supplementation improves mood in a double-blind crossover trial. Life Sci 2000;68:603-10. 1992;67(2):287-294. View abstract. Mahata, J., Argos, M., Verret, W., Kibriya, M. G., Santella, R. M., and Ahsan, H. Effect of selenium and vitamin e supplementation on plasma protein carbonyl levels in patients with arsenic-related skin lesions. View abstract. Psychopharmacology (Berl) 1990;102(4):549-550. Nutr.Health 2007;19(1-2):85-102. Gong HY, He JG, Li BS. View abstract. But selenium does not seem to improve, A pregnancy complication marked by high blood pressure and protein in the urine (pre-. Rao CV, Wang CQ, Simi B, et al. Radiat Oncol 2013;8:72. Cisplatin-induced changes of selenium levels and glutathione peroxidase activities in blood of testis tumor patients. Toxicol Appl Pharmacol 1998;152:309-14. 2019 Mar;98(9):e14733. View abstract. The deficiency can also affect the turnover rate of certain neurotransmitters ().In patients with Alzheimer’s, selenium concentration was found to be only 60% of that of healthy individuals ().Glutathione peroxidases, the important enzymes associated with selenium, are predominantly present in the brain. Serum selenium in children during anti-cancer chemotherapy. A randomized controlled trial. A., Breckler, L., Hale, J., Lehmann, H., Franklin, P., Lyons, G., Ching, S. Y., Mori, T. A., Barden, A., and Prescott, S. L. Supplementation with vitamins C, E, beta-carotene and selenium has no effect on anti-oxidant status and immune responses in allergic adults: a randomized controlled trial. View abstract. Kuklinski, B., Buchner, M., Schweder, R., and Nagel, R. [Acute pancreatitis--a free radical disease. Low selenium levels seem to be linked with an increased risk of developing osteoarthritis. View abstract. Eur.J Cancer 2004;40(11):1713-1723. Kamali A, Amirani E, Asemi Z. Butler, J. Song M, Kumaran MN, Gounder M, et al. 2003;12(5):464-467. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. Early evidence suggests that taking selenium supplements for 15 weeks might prevent bacterial skin infections in women with swelling in the arms and legs after breast cancer surgery. Arterioscler Thromb Vasc Biol 2001;21:1320-6. Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium. Ann Clin Biochem 1989;26 ( Pt 1):83-88. Baldew GS, Mol JG, de Kanter FJ, et al. Early research has found that taking selenium is linked with a lower risk of heart death in people with a specific type of dilated cardiomyopathy called Keshan disease. Selenium is a mineral that's essential to the body in trace amounts, mainly for synthesizing enzymes, but it can be toxic in large amounts. View abstract. Darlow, B. 2003;29(5):834-840. J Natl Cancer Inst 2003;95:1477-81.. View abstract. Crit Care. Schwingshackl L, Boeing H, Stelmach-Mardas M, et al. View abstract. A. and Austin, N. C. Selenium supplementation to prevent short-term morbidity in preterm neonates. Peretz, A., Neve, J., Desmedt, J., Duchateau, J., Dramaix, M., and Famaey, J. P. Lymphocyte response is enhanced by supplementation of elderly subjects with selenium-enriched yeast. Eur J Epidemiol. Thromb Res 1984;34:389-96. Most research shows that taking selenium does not reduce the risk of cancer or cancer-related death. Br J Nutr 2015;114(12):2039-45. This white color won’t grow upwards with the nail and is usually actually within the bed and the skin around it. Med Klin 9-15-1997;92 Suppl 3:42-45. Orndahl, G., Sellden, U., Hallin, S., Wetterqvist, H., Rindby, A., and Selin, E. Myotonic dystrophy treated with selenium and vitamin E. Acta Med Scand 1986;219(4):407-414. View abstract. Huston, R. K., Jelen, B. J., and Vidgoff, J. Selenium supplementation in low-birthweight premature infants: relationship to trace metals and antioxidant enzymes. Zinc metabolism in patients treated with captopril versus enalapril. A prospective study of plasma selenium levels and prostate cancer risk. Different selenium formulas and type of colon cancer might affect findings. View abstract. View abstract. Pol.Merkur Lekarski. Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT. View abstract. View abstract. Gerontology 2008;54(5):292-299. In this portion of HealthTap we provide health education but we can't provide treatment. 12-15-2004;37(5):1657-1663. View abstract. Vinceti M, Filippini T, Rothman KJ. HIV/AIDS. Perit.Dial.Int 2002;22(3):400-404. 2009;134(3):83-86. 2008;108(10):1636-1645. Although not all of these side effects may occur, if they do occur they may need medical attention. Czernichow, S., Couthouis, A., Bertrais, S., Vergnaud, A. C., Dauchet, L., Galan, P., and Hercberg, S. Antioxidant supplementation does not affect fasting plasma glucose in the Supplementation with Antioxidant Vitamins and Minerals (SU.VI.MAX) study in France: association with dietary intake and plasma concentrations. Yu, S. Y., Zhu, Y. J., Li, W. G., Huang, Q. S., Huang, C. Z., Zhang, Q. N., and Hou, C. A preliminary report on the intervention trials of primary liver cancer in high-risk populations with nutritional supplementation of selenium in China. Rajpathak S, Rimm E, Morris JS, Hu F. Toenail selenium and cardiovascular disease in men with diabetes. Organic selenium supplementation increases mercury excretion and decreases oxidative damage in long-term mercury exposed residents from Wanshan, China. View abstract. Wood, L. G., Fitzgerald, D. A., Lee, A. K., and Garg, M. L. Improved antioxidant and fatty acid status of patients with cystic fibrosis after antioxidant supplementation is linked to improved lung function. View abstract. Urinary selenium excretion in patients with cervical uterine cancer. Epub 2018 Jul 29. Selenium deficiency can cause Keshan disease (a type of heart disease) and male infertility. Ogawa, A., Ogawa, I., Obayashi, R., Umezu, K., Doi, M., and Hirao, T. Highly Selective Thioselenation of Vinylcyclopropanes with a (PhS)(2)-(PhSe)(2) Binary System and Its Application to Thiotelluration. Rayman MP, Thompson AJ, Bekaert B, et al. Accessed on June 26, 2020. West J Med 1990;153(2):160-167. View abstract. Cochrane.Database.Syst.Rev. View abstract. Osteoarthritis. [A comparative study of absorption of 2 organic selenium preparations and a placebo]. Bleys J, Navas-Acien A, Guallar E. Serum selenium and diabetes in U.S. adults. View abstract. Phytother Res 1993;7:285-9. Djujic IS, Jozanov-Stankov ON, Milovac M, et al. View abstract. Mazokopakis EE, Papadakis JA, Papadomanolaki MG, et al. Wang L, Wang J, Liu X, Liu Q, Zhang G, Liang L. Association between selenium intake and the risk of pancreatic cancer: a meta-analysis of observational studies. View abstract. A., Mandaliya, K., Emery, S., Lavreys, L., Ndinya-Achola, J. O., Bankson, D. D., Bwayo, J. J., and Kreiss, J. K. Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial. View abstract. JPEN J Parenter.Enteral Nutr 1991;15(5):556-559. But other research has found that selenium levels in the blood are not linked with the risk of cancer of the pancreas. Orndahl G, Grimby G, Grimby A, et al. Clark LC, Dalkin B, Krongrad A, et al. Trafikowska, A. W., Roberts, D. a controlled trial randomized clinical trial investigating the effect of very-low-dose on! Rate of preeclampsia after antioxidant supplementation in the general population and low energy stem! Li M, et al treatment with selenomethionine in patients with Hashimoto thyroiditis..., Davis RL, Shi Q, et al selenium enhances prostacyclin production cultured! Year of trying to conceive ( male infertility ), oxygen, and Adam, A. and... In rheumatoid arthritis is mixed S. A., Orlikov, G., Rindby, A., and,... Vital role in making antioxidant enzymes of selenium on mood and quality of:... 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